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Structure paper

TitleHuman FDPS synthase in complex with novel inhibitor
Journal, issue, pagesTo be Published
Publish dateSep 15, 2007 (structure data deposition date)
AuthorsEvdokimov, A.G. / Barnett, B.L. / Ebetino, F.H. / Pokross, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2rah:
Human FDPS synthase in complex with novel inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-11P:
[(7R)-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / mainly alpha / orthogonal bundle / osteoporosis / Cholesterol biosynthesis / Cytoplasm / Host-virus interaction / Isoprene biosynthesis / Lipid synthesis / Steroid biosynthesis / Sterol biosynthesis

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