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TitleCrystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295
Journal, issue, pagesTo Be Published
Publish dateJan 7, 2021 (structure data deposition date)
AuthorsKarim, M.R. / Schonbrunn, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.33 Å
Structure data

PDB-7lb0:
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

Chemicals

ChemComp-XXV:
1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / Bromodomain / TAF1 / TBP / transcription / general transcription factor IID / TFIID / TF250 / non-BET / ATR / kinase

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