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TitleStructural and molecular basis of kinaseregulated inner-kinetochore recruitment of PLK1 by CENP-U
Journal, issue, pagesTo be published
Publish dateMay 31, 2024 (structure data deposition date)
AuthorsRen, L. / Gasper, R. / Vetter, I.R. / Musacchio, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-9fjh:
Two PLK1 PBD proteins bound to CENP-U(58-114) phosphorylated at Thr78 and Thr98
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / PLK1 / CCAN / kinase / mitosis / kinetochore / CENP-U / phosphorylation

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