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TitleActivation of DNMT1 by Chemically Synthesized Dual monoubiquitinated PAF15 Protein
Journal, issue, pagesTo Be Published
Publish dateJan 5, 2024 (structure data deposition date)
AuthorsHayashi G / Takahashi Y / Kikuchi A / Kori S / Arita K / Murakami H
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.25 Å
Structure data

38573

8xqc

EMDB-38573, PDB-8xqc:
Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated PAF15 and hemimethylated DNA analog
Method: EM (single particle) / Resolution: 3.25 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSFERASE / DNA methyltransferase / protein-DNA complex / replication factor

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