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Structure paper

TitleCrystal structure of HSV1-TK complexed with Me-ARA-EdU
Journal, issue, pagesTo be Published
Publish dateFeb 10, 2014 (structure data deposition date)
AuthorsNeef, A.B. / Pernot, L. / Scapozza, L. / Luedkte, N.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-4oqx:
Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with Me-ARA-EdU
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EDV:
1-(2-deoxy-2-methyl-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione

ChemComp-HOH:
WATER

Source
  • human herpesvirus 1 (Herpes simplex virus type 1)
KeywordsTRANSFERASE / DNA SYNTHESIS / Thymidine kinase / ATP-Binding / nucleotide-binding / 5-ETHYNYLURIDINE NUCLEOSIDE DERIVATIVE

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