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Structure paper

TitleThe dynamic nature of hGSTA1-1 C-terminal helix
Journal, issue, pagesTo be published
Publish dateAug 29, 2017 (structure data deposition date)
AuthorsKumari, V. / Ji, X.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.55 - 2 Å
Structure data

PDB-6ato:
Crystal structure of hGSTA1-1 complexed with GSH and MPD in each subunit
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-6atp:
Crystal structure of apo-hGSTA1-1 exhibiting a new conformation of C-terminal helix
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6atq:
Crystal structure of apo-hGSTA1-1 exhibiting a new conformation of C-terminal helix
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GSH:
GLUTATHIONE

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Glutathione S-transferase / glutathione transferase / GST / hGSTA1-1 / GSH / apo

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