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TitleSynthesis and evaluation of tetrahydrobenzo[cd]indole derivatives as glycogen phosphorylase inhibitors
Journal, issue, pagesMed. Chem. Res., Year 2025
Publish dateJun 19, 2024 (structure data deposition date)
AuthorsArunrattiyakorn, P. / Juiprasert, C. / Koulas, S.M. / Boonsri, P. / Aree, T. / Yagi-Utsumi, M. / Kato, K. / Leonidas, D.D.
External linksMed. Chem. Res. / Search PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-9frm:
The crystal structure of glycogen phosphorylase with an indole derivative
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

PDB-1ifq:
Sec22b N-terminal domain

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE

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