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TitleFolding-Mediated Secretion of Pure Bispecific Antibodies
Journal, issue, pagesTo Be Published
Publish dateFeb 9, 2025 (structure data deposition date)
AuthorsTilegenova, C. / Liu, T. / Zhao, Q. / Are, M. / Zhao, Y. / Choi, W.S. / Bhaumik, A. / Steele, R. / Manieri, N. / Turegun, B. ...Tilegenova, C. / Liu, T. / Zhao, Q. / Are, M. / Zhao, Y. / Choi, W.S. / Bhaumik, A. / Steele, R. / Manieri, N. / Turegun, B. / Shaffer, P. / Ernst, R. / Sharma, S. / Cheung, W. / Zwolak, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-9n8q:
Crystal structure of Trastuzumab Fab with P151A
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HUMAN FAB FRAGMENT / IMMUNE RESPONSE / ProAla / Proline-to-alanine / bispecific antibody / bsAb / bsIgG / Cis-peptide / Trastuzumab / Fab

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