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Structure paper

TitleCrystal structure of the human LIMK1 kinase domain in complex with staurosporine
Journal, issue, pagesTo be Published
Publish dateMay 31, 2011 (structure data deposition date)
AuthorsBeltrami, A. / Chaikuad, A. / Daga, N. / Elkins, J.M. / Mahajan, P. / Savitsky, P. / Vollmar, M. / Krojer, T. / Muniz, J.R.C. / Fedorov, O. ...Beltrami, A. / Chaikuad, A. / Daga, N. / Elkins, J.M. / Mahajan, P. / Savitsky, P. / Vollmar, M. / Krojer, T. / Muniz, J.R.C. / Fedorov, O. / Allerston, C.K. / Yue, W.W. / Gileadi, O. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Knapp, S. / Bullock, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-3s95:
Crystal structure of the human LIMK1 kinase domain in complex with staurosporine
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-STU:
STAUROSPORINE / antibiotic*YM

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/ANTIBIOTIC / Structural Genomics / Structural Genomics Consortium / SGC / Protein Kinase / LIM domain kinase / TRANSFERASE-ANTIBIOTIC complex

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