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Structure paper

TitleStructure of KATP in complex with SpTx1
Journal, issue, pagesTo Be Published
Publish dateNov 8, 2024 (structure data deposition date)
AuthorsChen L / Wang M
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.87 - 2.88 Å
Structure data

EMDB-62311: Focus refined map of KATP core in complex with SpTx1
Method: EM (single particle) / Resolution: 2.88 Å

EMDB-62317: Focused refinement of SUR1 ABC module in complex with glibenclamide at 2.87 Angstrom
Method: EM (single particle) / Resolution: 2.87 Å

62322

9kgl

EMDB-62322, PDB-9kgl:
Structure of KATP channel in complex with centipede toxin SpTx1
Method: EM (single particle) / Resolution: 2.88 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-GBM:
5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide

Source
  • homo sapiens (human)
  • mesocricetus auratus (golden hamster)
  • scolopendra polymorpha (arthropod)
KeywordsTRANSPORT PROTEIN / KATP / Kir6.2 / SUR1 / Glibenclamide / SpTx1

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