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Structure paper

TitleStepwise Activation of SARM1 by a Biosynthetic NMN mimic
Journal, issue, pagesTo Be Published
Publish dateDec 17, 2024 (structure data deposition date)
AuthorsHuang Y / Zhang J / Zheng S / Wang X
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.83 - 3.55 Å
Structure data

62772

9l2d

EMDB-62772, PDB-9l2d:
Structure of SARM1 bound to M1 in the intermediate state 1
Method: EM (single particle) / Resolution: 2.83 Å

62774

9l2f

EMDB-62774, PDB-9l2f:
Structure of SARM1 bound to M1 and 1AD in the active state
Method: EM (single particle) / Resolution: 3.55 Å

62775

9l2g

EMDB-62775, PDB-9l2g:
Structure of SARM1 2C-mutant bound to M1
Method: EM (single particle) / Resolution: 3.27 Å

Chemicals

PDB-1eiv:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / NAD(+) hydrolase / cell death / apoptosis

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