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TitleCrystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
Journal, issue, pagesTo Be Published
Publish dateFeb 22, 2023 (structure data deposition date)
AuthorsMechaly, A.E. / Zhang, W. / Haouz, A. / Green, M. / Rodrigues-Lima, F.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.463 Å
Structure data

PDB-8cna:
Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.463 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-01K:
[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / histone acetyltransferase

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