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Structure paper

TitleUV lesion binding and repair inhibition by ETS-family transcription factors
Journal, issue, pagesTo Be Published
Publish dateOct 13, 2025 (structure data deposition date)
AuthorsSivapragasam, S. / Terrell, J.R. / Germann, M.W. / Morledge-Hampton, B. / Adhikari, S.P. / Brown, M. / Hrdlicka, P.J. / Wyrick, J.J. / Poon, G.M.K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-9ynz:
Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGGAAGTGGG-3') d(5'-TCCCACT*CPD*CGCTTAT-3')
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / transcription factor / protein-DNA complex / ETS family / ETS / PU.1 / TRANSCRIPTION-DNA complex / DNA mismatch

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