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TitleCrystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
Journal, issue, pagesto be published
Publish dateNov 13, 2012 (structure data deposition date)
AuthorsYang, M. / Li, J. / He, J.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.649 Å
Structure data

PDB-4hy6:
Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
Method: X-RAY DIFFRACTION / Resolution: 1.649 Å

Chemicals

ChemComp-FJ1:
6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsChaperone/Chaperone Inhibitor / ATP Binding / molecularchaperone / inhibitor / Rossmann Fold / molecular chaperone / ATP hydrolysis / Chaperone-Chaperone Inhibitor complex

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