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TitlePharmacological and structural characterization of vibostolimab, a novel anti-human TIGIT blocking antibody for cancer immunotherapy
Journal, issue, pagesTo Be Published
Publish dateJan 26, 2024 (structure data deposition date)
AuthorsFischmann, T.O. / Malashock, D. / Wang, H. / Grein, J. / Bahmanjah, S. / Ban, D. / Chien, E. / Hsieh, M. / Mayhood, T. / Yuan, J. ...Fischmann, T.O. / Malashock, D. / Wang, H. / Grein, J. / Bahmanjah, S. / Ban, D. / Chien, E. / Hsieh, M. / Mayhood, T. / Yuan, J. / Beaumont, M. / Baker, J. / McCoy, M.A. / Wilson, D. / Williams, S.M.G. / Blumenschein, W. / Fayadat-Dilman, L. / Seghezzi, W. / Keenan, T. / Han, J.-H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-8vte:
Co-structure of the Fab of the anti-TIGIT Vibostolimab antibody with its antigen
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody TIGIT immunotherapy

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