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Structure paper

TitleCrystal structure of mouse CARM1 in complex with inhibitor SA0435
Journal, issue, pagesTo Be Published
Publish dateMar 15, 2016 (structure data deposition date)
AuthorsCura, V. / Marechal, N. / Mailliot, J. / Troffer-Charlier, N. / Wurtz, J.M. / Bonnefond, L. / Cavarelli, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5isb:
Crystal structure of mouse CARM1 in complex with inhibitor SA0435
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-6CX:
5'-{[(3S)-3-amino-3-carboxypropyl][(1H-imidazol-4-yl)methyl]amino}-5'-deoxyadenosine

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-M2M:
1-METHOXY-2-(2-METHOXYETHOXY)ETHANE

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / PROTEIN ARGININE METHYLTRANSFERASE / CATALYTIC DOMAIN / CHROMATIN REGULATOR / MRNA PROCESSING / MRNA SPLICING / NUCLEUS / S-ADENOSYL-L-METHIONINE / TRANSCRIPTION / TRANSCRIPTION REGULATION

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