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TitleCrystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand
Journal, issue, pagesTo be Published
Publish dateNov 25, 2013 (structure data deposition date)
AuthorsFilippakopoulos, P. / Picaud, S. / Felletar, I. / Martin, S. / Fedorov, O. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.73 Å
Structure data

PDB-4nqn:
Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-Y1Z:
2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/INHIBITOR / STRUCTURAL GENOMICS CONSORTIUM / SGC / BROMODOMAIN / INHIBITION / Transcription / Small molecule inhibitor / TRANSCRIPTION-INHIBITOR complex

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