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Structure paper

TitleStructural Basis for the Modulation of Ryanodine Receptor by Dantrolene and Azumolene
Journal, issue, pagesTo Be Published
Publish dateDec 28, 2024 (structure data deposition date)
AuthorsHadiatullah, H. / Lin, L. / Yuchi, Z.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.97 - 3 Å
Structure data

PDB-9l90:
The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and AMP-PCP
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-9l91:
The crystal structure of human RyR3 Repeat12 domain in complex with Azumolene and AMP-PCP
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-9l92:
The crystal structure of human RyR3 Repeat12 domain
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-9l9b:
The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

PDB-9ls7:
The crystal structure of human RyR3 Repeat12 domain complex with RI-2 and AMP-PCP
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

Chemicals


ChemComp, No image

ChemComp-U1C:
Unknown entry

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

PDB-1l7b:
Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT

ChemComp-GOL:
GLYCEROL

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

PDB-1l7g:
Crystal structure of E119G mutant influenza virus neuraminidase in complex with BCX-1812

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Repeat12 domain / dantranlene / AMP-PCP / ryanodine receptor / Azumolene / apo / ADP

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