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TitleCrystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with dihydroorotate
Journal, issue, pagesTo be Published
Publish dateDec 26, 2006 (structure data deposition date)
AuthorsInaoka, D.K. / Shimizu, H. / Sakamoto, K. / Shiba, T. / Kurisu, G. / Nara, T. / Aoki, T. / Harada, S. / Kita, K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.38 Å
Structure data

PDB-2e68:
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with dihydroorotate
Method: X-RAY DIFFRACTION / Resolution: 1.38 Å

Chemicals

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-DOR:
(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • trypanosoma cruzi (eukaryote)
KeywordsOXIDOREDUCTASE / Chagas disease / Pyrimidine Biosynthesis / Dihydroorotate Dehydrogenase / Fumarate Reductase / Energy Metabolism / Redox Homeostasis / Flavoprotein

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