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TitleIdentification of a cryptic allosteric site on the E3 ligase adapter protein cereblon
Journal, issue, pagesNature, Year 2025
Publish dateMay 22, 2025 (structure data deposition date)
AuthorsRizvi Z / Dippon VN / Choudhry AE / Chung CW / Alkuraya AF / Xu W / Tao XB / Jurewicz AJ / Schneck JL / Chen W ...Rizvi Z / Dippon VN / Choudhry AE / Chung CW / Alkuraya AF / Xu W / Tao XB / Jurewicz AJ / Schneck JL / Chen W / Curnutt NM / Kabir F / Chan KH / Queisser MA / Musetti C / Dai H / Benowitz AB / Woo CM / Lander GC
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.52 Å
Structure data

EMDB-70776: DDB1-CRBN open NU refine map
Method: EM (single particle) / Resolution: 2.52 Å

Source
  • Homo sapiens (human)

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