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-Structure paper
Title | The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole |
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Journal, issue, pages | To be Published |
Publish date | Mar 5, 2014 (structure data deposition date) |
![]() | Shang, N. / Li, Q. / Huang, C.H. / Oldfield, E. / Guo, R.T. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.9 Å |
Structure data | ![]() PDB-3wsa: ![]() PDB-3wsb: |
Chemicals | ![]() ChemComp-RWZ: ![]() ChemComp-HOH: ![]() ChemComp-FPS: |
Source |
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![]() | TRANSFERASE / isoprenoids / drug discovery / human squalene synthase / SQ-109 / TRANSFERASE/TRANSFERASE INHIBITOR / Trypanosoma cruzi squalene synthase / SQ109 / FSPP / TRANSFERASE-TRANSFERASE INHIBITOR complex |