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TitleCrystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S))
Journal, issue, pagesTo Be Published
Publish dateJun 6, 2022 (structure data deposition date)
AuthorsKlima, M. / Smola, M. / Boura, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-8a2x:
Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S))
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-KZA:
9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine

Source
  • homo sapiens (human)
KeywordsANTIVIRAL PROTEIN / sting / antiviral / activator

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