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Structure paper

TitleStructure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
Journal, issue, pagesNat Commun, Vol. 9, Page 4679-4691, Year 2018
Publish dateSep 14, 2018 (structure data deposition date)
AuthorsKimberlin, C.R. / Chin, S.M. / Roe-Zurz, Z. / Zhang, P. / Xu, A. / Liao-Chan, S. / Debasish, S. / Nager, A.R. / Schirle Oakdale, N. / Brown, C. ...Kimberlin, C.R. / Chin, S.M. / Roe-Zurz, Z. / Zhang, P. / Xu, A. / Liao-Chan, S. / Debasish, S. / Nager, A.R. / Schirle Oakdale, N. / Brown, C. / Wang, F. / Yang, Y. / Lindquist, K. / Yeung, Y.A. / Salek-Ardakani, S. / Chaparro-Riggers, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.13 Å
Structure data

PDB-6mgp:
Structure of human 4-1BB / 4-1BBL complex
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Signaling / TNFRSF / TNFSF / 4-1BB / CD137 / 4-1BBL / CD137L / complex

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