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Author
Journal
IF

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Structure paper

Titlep53 dynamics vary between tissues and are linked with radiation sensitivity
Journal, issue, pagesTo be published
Publish dateNov 1, 2018 (structure data deposition date)
AuthorsOrnstein, J. / Iwamoto, Y. / Prytyskach, M. / Miller, M. / Kallen, J. / Ferretti, S. / Holzer, P. / Forrester, W. / Weissleder, R. / Lahav, G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6i29:
X-ray structure of the p53-MDM2 inhibitor NMI801 bound to HDM2 at 2.1A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-H0W:
6-chloranyl-3-[3-[(1~{S})-1-(4-chlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-~{N}-[2-[4-(2-oxidanylidene-1,3-oxazinan-3-yl)piperidin-1-yl]pyridin-3-yl]-1~{H}-indole-2-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / LEAD OPTIMIZATION

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