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-Structure paper
Title | Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening |
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Journal, issue, pages | To Be Published |
Publish date | Dec 16, 2020 (structure data deposition date) |
Authors | Chiew, B. / Scanlon, M.J. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.07 - 2.26 Å |
Structure data | PDB-7l23: PDB-7lqp: |
Chemicals | ChemComp-SO4: ChemComp-IOD: ChemComp-XFS: ChemComp-HOH: ChemComp-YAV: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Inhibitor / HIV Integrase / TRANSFERASE-TRANSFERASE INHIBITOR complex / TRANSFERASE/INHIBITOR / TRANSFERASE-INHIBITOR complex |