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TitlePim1 in complex with (E)-3-(2-(thiophen-2-yl)vinyl)-3,4-dihydroquinoxalin-2(1H)-one and Pimtide
Journal, issue, pagesTo Be Published
Publish dateOct 31, 2023 (structure data deposition date)
AuthorsHochban, P.M.M. / Heyder, L. / Heine, A. / Diederich, W.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.88 Å
Structure data

PDB-8r0h:
Pim1 in complex with (E)-3-(2-(thiophen-2-yl)vinyl)-3,4-dihydroquinoxalin-2(1H)-one and Pimtide
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-8UB:
3-(2-thiophen-2-ylethenyl)-1~{H}-quinoxalin-2-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SERINE KINASE / KINASE / COMPLEX / PIM1 / PIM / PIM-1 / INHIBITOR / TUMORIGENISIS / CANCER / PIMTIDE / PROTO ONCOGEN / ATP / PHOSPHORYLATION / APOPTOSIS / CELL CYCLE

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