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TitleSelective NSD2 Inhibition Reveals an Epigenetic Dependency of KRAS-Driven Cancers
Journal, issue, pagesNature, Year 2025
Publish dateJul 29, 2024 (structure data deposition date)
AuthorsSzczepski, K. / Jaremko, L.
External linksSearch PubMed
MethodsNMR (solution)
Structure data

PDB-9cvd:
SET Domain of Histone-Lysine N-Methyltransferase NSD2 in Complex with Selective Inhibitor
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

PDB-1a0m:
1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Methyltransferase / Complex / Inhibition / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR complex

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