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TitleDiscovery of a SMARCA2/4 ATPase Inhibitors Suitable for Use in SMARCA4-mutant Preclinical Models
Journal, issue, pagesTo Be Published
Publish dateMar 8, 2024 (structure data deposition date)
AuthorsAlford, J. / Farrow, N.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-9ayq:
SMARCA2 in complex with a pyridine-2-one-based inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

PDB-1ahq:
RECOMBINANT ACTOPHORIN

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Helicase

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