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Structure paper

TitleStructural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
Journal, issue, pagesTo be Published
Publish dateMay 28, 2010 (structure data deposition date)
AuthorsCampeotto, I. / Bolt, A.H. / Harman, T.A. / Dennis, C. / Trinh, C.H. / Phillips, S.E.V. / Nelson, A. / Pearson, A.R. / Berry, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-2xfw:
Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-PYR:
PYRUVIC ACID

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsLYASE

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