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TitleCofactor-mimicking HIV-1 capsid inhibitors, and their escape mutants, drive innate immune sensing
Journal, issue, pagesTo Be Published
Publish dateAug 1, 2025 (structure data deposition date)
AuthorsGovasli, M.A.L. / Pinotsis, N. / Towers, G. / Selwood, D. / Jacques, D.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.074 Å
Structure data

PDB-9s6w:
HIV-1 capsid (M-group) - native in complex with JW3-100
Method: X-RAY DIFFRACTION / Resolution: 2.074 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-CL:
Unknown entry

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-1PG:
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL

PDB-1jl5:
Novel Molecular Architecture of YopM-a Leucine-rich Effector Protein from Yersinia pestis

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 (new york-5 isolate)
KeywordsVIRAL PROTEIN / Hexameric HIV-1 (M-group)

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