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Structure paper

Titlehydantoin derivatives as Non-pepridic inhibitors of Ras Farnesyl transferase
Journal, issue, pagesTo be published
Publish dateNov 14, 2005 (structure data deposition date)
AuthorsLee, J. / Kim, J. / Koh, J.S. / Chung, H.H. / Ro, S. / Kim, K.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2f0y:
Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and hydantoin derivative
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-FPP:
FARNESYL DIPHOSPHATE

ChemComp-3MN:
3-({3-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-5-(1-NAPHTHYL)-2,4-DIOXOIMIDAZOLIDIN-1-YL}METHYL)BENZONITRILE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / farnesyltransferase

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