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TitlePreclinical assessment of an investigational mRNA lipid nanoparticle OspA vaccine for Lyme disease
Journal, issue, pagesTo Be Published
Publish dateJun 25, 2024 (structure data deposition date)
AuthorsFinn, M.B. / Dold, C. / Willsey, G. / Piazza, C.L. / Clendenen, L. / Shrestha, M. / You, S.S. / Ma, L. / Dhingra, Y. / Laciak, A.R. ...Finn, M.B. / Dold, C. / Willsey, G. / Piazza, C.L. / Clendenen, L. / Shrestha, M. / You, S.S. / Ma, L. / Dhingra, Y. / Laciak, A.R. / Uggowitzer, K.A. / Obiero, J.M. / Natarajan, H. / Green, S. / Pirayesh, E. / Lai, Y.-T. / Himansu, S. / Carfi, A. / Hu, L.T. / Mantis, N. / Plante, O.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-9cds:
Crystal structure of OspA ST1 from B. burgdorferi bound to monoclonal antibody LA-2
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • borreliella burgdorferi b31 (bacteria)
KeywordsIMMUNE SYSTEM / Lyme disease / Outer Surface Protein A (OspA)

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