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Structure paper

TitleStructure of Tdp1 catalytic domain in complex with compound XZ520
Journal, issue, pagesTo Be Published
Publish dateNov 2, 2018 (structure data deposition date)
AuthorsLountos, G.T. / Zhao, X.Z. / Kiselev, E. / Tropea, J.E. / Needle, D. / Burke Jr., T.R. / Pommier, Y. / Waugh, D.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.661 Å
Structure data

PDB-6myz:
Crystal structure of Tdp1 catalytic domain in complex with compound XZ520
Method: X-RAY DIFFRACTION / Resolution: 1.661 Å

Chemicals

ChemComp-K7D:
4-oxo-8-phenyl-1,4-dihydroquinoline-3-carboxylic acid

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / fragment based drug design / anti-cancer drug design / DNA BINDING PROTEIN

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