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Structure paper

TitleStructural mechanism of inhibitor-resistance by ERK2 mutations
Journal, issue, pagesBiodesign, Vol. 9, Page 14-18, Year 2021
Publish dateFeb 25, 2021 (structure data deposition date)
AuthorsPark, Y. / Kim, M. / Ryu, S.E.
External linksBiodesign / Search PubMed
MethodsX-ray diffraction
Resolution2.28 - 2.481 Å
Structure data

PDB-7e73:
Crystal structure of human ERK2 mutant (Y36H)
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

PDB-7e75:
Crystal structure of human ERK2 mutant (G37C)
Method: X-RAY DIFFRACTION / Resolution: 2.481 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase

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