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TitleCrystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111.
Journal, issue, pagesTo be published
Publish dateJun 15, 2023 (structure data deposition date)
AuthorsZeng, H. / Dong, A. / Brown, P.J. / Arrowsmith, C.H. / Edwards, A.M. / Halabelian, L. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-8t68:
Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE


ChemComp, No image

ChemComp-ZKI:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / TRANSFERASE/INHIBITOR / SET domain / Methyltransferase / SGC / SUV420H1 / TRANSFERASE-INHIBITOR complex

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