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Structure paper

TitleOptimization of a scFv-based biotherapeutic by CDR side-chain clash repair
Journal, issue, pagesTo Be Published
Publish dateJun 15, 2015 (structure data deposition date)
AuthorsTu, C. / Terrabube, V. / Tam, A. / Stochaj, W. / Fennell, B. / Lin, L. / Stahl, M. / LaVallie, E. / Somers, W. / Finlay, W. ...Tu, C. / Terrabube, V. / Tam, A. / Stochaj, W. / Fennell, B. / Lin, L. / Stahl, M. / LaVallie, E. / Somers, W. / Finlay, W. / Mosyak, L. / Bard, J. / Cunningham, O.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.4049 - 1.54 Å
Structure data

PDB-5c2b:
anti-CXCL13 parental scFv - 3B4
Method: X-RAY DIFFRACTION / Resolution: 1.4049 Å

PDB-5c6w:
anti-CXCL13 scFv - E10
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / anti-CXCL13 / scFv

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