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Titlec-KIT kinase domain in complex with crenolanib
Journal, issue, pagesTo Be Published
Publish dateFeb 15, 2024 (structure data deposition date)
AuthorsTeuber, A. / Niggenaber, J. / Kleinboelting, S.B. / Landel, I. / Warmuth, J. / Busick, D. / Mueller, M.P. / Bauer, S. / Rauh, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-8s1a:
c-KIT kinase domain in complex with crenolanib
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-6T2:
1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / stem cell factor receptor / inhibitor / GIST / resistance / KIT / crenolanib

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