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Structure paper

TitleStructural basis for blockage of DNA synthesis by a thymine dimer lesion in a high-fidelity DNA polymerase
Journal, issue, pagesTo Be Published
Publish dateSep 23, 2019 (structure data deposition date)
AuthorsWalsh, A.R. / Beese, L.S. / Wu, E.Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-6ueu:
Crystal structure of BF DNA polymerase F710Y mutant bound to tetrahydrofuran and dATP
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • geobacillus stearothermophilus (bacteria)
  • synthetic construct (others)
KeywordsREPLICATION

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