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TitleCrystal structure of human Urokinase-type plasminogen activator in complex with bicycle peptide inhibitor UK970
Journal, issue, pagesTo Be Published
Publish dateMay 5, 2022 (structure data deposition date)
AuthorsCaregnato, A. / Angela, P. / Mazzoccato, Y. / Frasson, N. / Angelini, A. / Cendron, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-7zrt:
Crystal structure of human Urokinase-type plasminogen activator in complex with bicycle peptide inhibitor UK970
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-ZBR:
1,3,5-tris(bromomethyl)benzene

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE / Urokinase-type plasminogen activator / Serine protease / Plasminogen Activator

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