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Structure paper

TitleCrystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand
Journal, issue, pagesTO BE PUBLISHED
Publish dateJul 12, 2011 (structure data deposition date)
AuthorsFilippakopoulos, P. / Picaud, S. / Felletar, I. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.975 Å
Structure data

PDB-3svf:
Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand
Method: X-RAY DIFFRACTION / Resolution: 1.975 Å

Chemicals

ChemComp-WDR:
(4S)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-(2-hydroxyethoxy)-3-methyl-3,4-dihydroquinazolin-2(1H)-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsUNKNOWN FUNCTION / Bromodomain / Structural Genomics / Structural Genomics Consortium / SGC

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