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Structure paper

TitleHuman genetics guides the discovery of novel CARD9 inhibitors with anti-inflammatory activity in vitro as well as in vivo
Journal, issue, pagesTo be published
Publish dateMar 4, 2024 (structure data deposition date)
AuthorsRaymond, D.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.79 - 2.726 Å
Structure data

PDB-9avm:
Crystal Structure of CARD9 coiled-coil K156-K214
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-9avn:
Crystal Structure of CARD9 coiled-coil K156-K214 bound to Compound 1
Method: X-RAY DIFFRACTION / Resolution: 2.726 Å

Chemicals

ChemComp-HOH:
WATER

PDB-1ag7:
CONOTOXIN GS, NMR, 20 STRUCTURES

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Adapter protein

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