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TitleCrystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114
Journal, issue, pagesto be published
Publish dateFeb 28, 2017 (structure data deposition date)
AuthorsMayclin, S.J. / Abendroth, J. / Lorimer, D.D. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5v0x:
Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MYA:
TETRADECANOYL-COA

ChemComp-8RD:
{4-[2-(5-fluoro-2-{3-[(methylamino)methyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}phenoxy)ethyl]-1,5-dimethyl-1H-pyrazol-3-yl}(morpholin-4-yl)methanone

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • plasmodium vivax (malaria parasite P. vivax)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / SSGCID / glycylpeptide N-tetradecanoyltransferase / N-myristoyltransferase / NMT / Plasmodium vival / Salvador I / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / TRANSFERASE-TRANSFERASE INHIBITOR complex

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