+Search query
-Structure paper
Title | Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitor |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 30, Page 127292-127298, Year 2020 |
Publish date | Apr 2, 2020 (structure data deposition date) |
Authors | Ruiz, V.G. / Czyzyk, D.J. / Kumar, V.P. / Jorgensen, W.L. / Anderson, K.S. |
External links | Bioorg. Med. Chem. Lett. / Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.79 Å |
Structure data | PDB-6wep: |
Chemicals | ChemComp-NDP: ChemComp-MTX: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE / TS / TS-DHFR |