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Structure paper

TitleStructure of TDP1 complexed with compound IB09
Journal, issue, pagesTo Be Published
Publish dateMar 18, 2024 (structure data deposition date)
AuthorsLountos, G.T. / Zhao, X.Z. / Barakat, I. / Wang, W. / Agama, K. / Al Mahmud, M.R. / Pommier, Y. / Burke, T.R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.62 Å
Structure data

PDB-9b3b:
Structure of TDP1 complexed with compound IB09
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

PDB-1aim:
CRUZAIN INHIBITED BY BENZOYL-TYROSINE-ALANINE-FLUOROMETHYLKETONE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / phosphodiesterase / drug target / cancer

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