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TitleCrystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa
Journal, issue, pagesto be published
Publish dateSep 12, 2022 (structure data deposition date)
AuthorsAbendroth, J. / Horanyi, P.S. / Hill, P. / Lorimer, D.D. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-8egm:
Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with compound AZ13644908
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-WIU:
(2R)-2-({4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)-2-phenylethyl (2-aminoethyl)carbamate

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa pao1 (bacteria)
KeywordsLIGASE / SSGCID / murC / UDP-N-acetylmuramoyl-L-alanine synthetase / Cell wall biogenesis / peptidoglycan biosynthesis / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease

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