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Author
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IF

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Structure paper

TitlehPDE4D2 structure with inhibitor NPD-654
Journal, issue, pagesTo be published
Publish dateAug 30, 2020 (structure data deposition date)
AuthorsSingh, A.K. / Brown, D.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.24 Å
Structure data

PDB-7a8q:
Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-654
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-R4H:
2-cycloheptyl-5-[4-methoxy-3-[[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]methoxy]phenyl]-4,4-dimethyl-pyrazolidin-3-one

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Phosphodiesterase / cAMP hydrolysis / alternative splicing

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