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Structure paper

TitleMutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation
Journal, issue, pagesCommun Biol, Vol. 2, Year 2019
Publish dateMar 3, 2015 (structure data deposition date)
AuthorsChen, T.J. / Wang, H.J. / Liu, J.S. / Cheng, H.H. / Hsu, S.C. / Wu, M.C. / Lu, C.H. / Wu, Y.F. / Wu, J.W. / Liu, Y.Y. ...Chen, T.J. / Wang, H.J. / Liu, J.S. / Cheng, H.H. / Hsu, S.C. / Wu, M.C. / Lu, C.H. / Wu, Y.F. / Wu, J.W. / Liu, Y.Y. / Kung, H.J. / Wang, W.C.
External linksCommun Biol / Search PubMed
MethodsX-ray diffraction
Resolution2.41 Å
Structure data

PDB-4yj5:
Crystal structure of PKM2 mutant
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-PYR:
PYRUVIC ACID

ChemComp-MG:
Unknown entry

ChemComp-SER:
SERINE

ChemComp-FBP:
1,6-di-O-phosphono-beta-D-fructofuranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PKM2 mutant

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