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Structure paper

TitleInner channel lipids regulated gating mechanism of human pannexins.
Journal, issue, pagesTo Be Published
Publish dateSep 23, 2022 (structure data deposition date)
AuthorsCong Y / Jin X / Kong F / Wu T / Yan C
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.4 - 3.8 Å
Structure data

34374

8gyo

EMDB-34374: Inner channel lipids regulated gating mechanism of human pannexins
PDB-8gyo: Inner channel lipids regulated gating mechanism of human pannexins.
Method: EM (single particle) / Resolution: 3.8 Å

34375

8gyp

EMDB-34375: Cryo-EM structure of human Pannexin-3 in closed state
PDB-8gyp: Cryo-EM structure of human Pannexin-3 in closed state.
Method: EM (single particle) / Resolution: 3.5 Å

34376

8gyq

EMDB-34376: Cryo-EM structure of human Pannexin-2 in pre-open state
PDB-8gyq: Cryo-EM structure of human Pannexin-2 in pre-open state.
Method: EM (single particle) / Resolution: 3.4 Å

34377

8gyt

EMDB-34377: Cryo-EM structure of human Pannexin-3 R36S/F40R variant in pre-open state
PDB-8gyt: Cryo-EM structure of human Pannexin-3 R36S/F40R variant in pre-open state.
Method: EM (single particle) / Resolution: 3.68 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-AJP:
Digitonin / detergent*YM

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Pannexin / ATP / Inner channel lipids / Cell-cell communication

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