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TitleThe ZnF-UBP domain regulates USP16 activity by dislodging ubiquitin from the active site
Journal, issue, pagesTo Be Published
Publish dateSep 18, 2025 (structure data deposition date)
AuthorsAlexandrovics, J.A. / Agrata, R. / Schenk, P. / Cerra, A. / Nachbur, U. / Babon, J.J. / Komander, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-9yc2:
Crystal structure of USP49 ZnF-UBP domain
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / USP49 / deubiquitinase / DUB / protease / ubiquitin / histone / nucleosome / ubiquitin binding domain

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