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TitleCrystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-322
Journal, issue, pagesTo Be Published
Publish dateAug 17, 2020 (structure data deposition date)
AuthorsKarim, M.R. / Schonbrunn, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-7jtc:
Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-322
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-VK1:
1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(methylsulfanyl)pyrimidin-4-yl}cyclopropane-1-sulfonimidoamide

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / Bromodomain / TAF1 / non-BET / BET / kinase inhibitor / ATR / dual BRD-kinase

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